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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1761071Generated: October 30, 2026

N,1-dimethylindole-2-carboxamide → [(5-Fluoro-1H-indol-2-yl)methyl]-methylamine

https://huagongshe.com/reaction/1761071

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,1-dimethylindole-2-carboxamideHCID 12303315—
ReactantN,1-Dimethyl-5-fluoro-1H-indole-2-carboxamideHCID 22593743—
Product[(5-Fluoro-1H-indol-2-yl)methyl]-methylamineHCID 2259372678%

Reaction Steps

According to the procedure of Preparation 1(c), except substituting N,1-dimethyl-5-fluoro-1H-indole-2-carboxamide for the N, 1-dimethyl-1H-indole-2-carboxamide, the title compound (1.5 g, 78%) was prepared as a white solid: MS (ES) t/e 193 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06846819B1
Source datasetuspto-grants-2005_01
ORD IDord-65294af0a1104efdad214a04ccfaa7b5
Source noteuspto-grants-2005_01