benzyl (E)-3-(6-aminopyridin-3-yl)acrylate → HCID 22593750, compound

HRID 1761077Notes

Reaction equation

HRID 1761077 reaction equation
[CH3:1][N:2]([CH3:14])[C:3]1[N:8]=[CH:7][C:6]([C:9](=[CH2:13])C([O-])=O)=[CH:5][CH:4]=1.NC1N=CC(/C=C/[C:24]([O:26]CC2C=CC=CC=2)=[O:25])=CC=1>>[CH3:14][N:2]([CH3:1])[C:3]1[N:8]=[CH:7][C:6](/[CH:9]=[CH:13]/[C:24]([OH:26])=[O:25])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 11128853benzyl (E)-3-(6-aminopyridin-3-yl)acrylateHCID 131724716HCID 131724716, compound

Product 1

HCID 22593750HCID 22593750, compoundYield 36%

Procedure

According to the procedure of Preparation 2 (b), except substituting benzyl (E)-3-[6-(dimethylamino)pyridin-3-yl-acrylate for benzyl (E)-3-(6-aminopyridin-3-yl)acrylate, the title compound (0.20 g, 36%) was prepared as a white solid: MS (ES) m/e 193 (M+H)+.

Sources & evidence

ORD record
ord-2ec5e462ee73495f906adfe6b5b6e99e
Source dataset
uspto-grants-2005_01
Patent number
US06846819B1

Reaction notes

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