HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Nitro-2-oxindole → 5-Amino-2-oxindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Nitro-2-oxindole | HCID 230366 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Amino-2-oxindole | HCID 2773213 | 60% |
Reaction Steps
5-Nitro-1,3-dihydro-indol-2-one (6.3 g) was hydrogenated in methanol over 10% palladium on carbon to give 3.0 g (60% yield) of 5-amino-1,3-dihydro-indol-2-one as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06846839B1 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-d5b6633404614ef6935da85b05aaceb0 |
| Source note | uspto-grants-2005_01 |