HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanediacetic acid → 3-Azaspiro(5.5)undecane-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanediacetic acid | HCID 78061 | — |
| Reactant | Acetic anhydride ammonium acetate | HCID 131724721 | — |
| Product | 3-Azaspiro(5.5)undecane-2,4-dione | HCID 14324 | — |
Reaction Steps
Reaction of a mixture of acetic anhydride/ammonium acetate with 1,1-cyclohexane diacetic acid at 160° C.-170° C., followed by precipitation of the product by gradual cooling and treatment with water/secondary butyl alcohol, and subsequent filtration to yield 3,3-pentamethylene glutarimide;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06846950B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-7de42d904d544738ad9a306b8f8f0090 |
| Source note | uspto-grants-2005_01 |