p-Toluenesulfonic acid → HCID 86742967, compound

Participants

Reaction Steps

Proteinaceous Emulsifier 13 was prepared by using L-leucine in place of L-alanine. Specifically, L-leucine myristyl ester p-toluenesulfonate was synthesized in the same manner as described in Example 18 for the synthesis of an L-alanine ester p-toluenesulfonate, except that L-leucine was used in place of L-alanine. The resulting p-toluenesulfonate was dissolved in 200 ml of benzene, and this solution was treated three times with 300-ml portions of 0.1N NaOH. Thereafter, the benzene layer was isolated and washed thoroughly with water. After washing with water, the benzene layer was isolated and dried overnight over anhydrous sodium sulfate. After drying, the benzene layer was filtered and the resulting benzene solution was evaporated to remove the solvent. Thus, purified L-leucine myristyl ester was obtained in the form of an oily material. Using this ester, an enzymatic reaction was carried out in the same manner as in Example 18 to obtain Proteinaceous Emulsifier 13.

Provenance & Evidence