Water → HCID 14303119, compound

Participants

Reaction Steps

12.3 g (0.5 mol) of 3-(3-trifluoromethyl-phenoxy)-3-methyl-butan-2-one are heated under reflux together with 110 g (1 mol) of 3-chloropropanediol and 10 g of acid ion exchanger (Lewasorb A10) in 600 ml of toluene over a water separator for 14 hours. The cooled reaction mixture is filtered and the filtrate is dried over sodium sulphate and concentrated. The residue is distilled under a high vacuum. 109 g (65% of theory) of 2-[2-(3-trifluoromethyl-phenoxy)-prop-2-yl]-2-methyl-4-chloromethyl-1,3-dioxolane of boiling point 163° C. under 0.2 mbar are obtained.

Provenance & Evidence