(1,2,4)Triazolo(1,5-a)pyridine → HCID 14051011, compound

HRID 1761432Notes

Reaction equation

HRID 1761432 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:31]/[O:32][CH3:33])/[C:8]([NH:10][C@@H:11]2[C:29](=[O:30])[N:13]3[C:14]([C:26]([OH:28])=[O:27])=[C:15]([CH2:18]OC(=O)CC(=O)C)[CH2:16][S:17][C@H:12]23)=[O:9])[N:6]=1.[N:34]1[CH:35]=[N:36][N:37]2[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=12>>[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:31]/[O:32][CH3:33])/[C:8]([NH:10][C@@H:11]2[C:29](=[O:30])[N:13]3[C:14]([C:26]([O-:28])=[O:27])=[C:15]([CH2:18][N+:34]4[CH:35]=[N:36][N:37]5[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=45)[CH2:16][S:17][C@H:12]23)=[O:9])[N:6]=1

Participants

3

Reactant 2

HCID 67508(1,2,4)Triazolo(1,5-a)pyridineHCID 13457845HCID 13457845, compound

Product 1

HCID 14051011HCID 14051011, compound

Procedure

7β(2-(2-Aminothiazole-4-yl)-2(Z)-methoxyiminoacetamido]-3-(3-oxobutyryloxymethyl)-3-cephem-4-carboxylic acid and [1,2,4]triazolo[1,5-a]pyridine are treated in a way analogous to that in Example 1 to yield the desired compound.

Sources & evidence

ORD record
ord-68909f0f5104430daec1ea7a1305a41b
Source dataset
uspto-grants-1989_05
Patent number
US04826834

Reaction notes

Loading…