HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentane-1,1-diacetic anhydride → 8-Hydroxy-8-azaspiro[4.5]decane-7,9-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentane-1,1-diacetic anhydride | HCID 79743 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 8-Hydroxy-8-azaspiro[4.5]decane-7,9-dione | HCID 14280582 | — |
Reaction Steps
A solution of 8-oxaspiro[4.5]decan-7,9-dione (5.0 g) and hydroxylamine hydrochloride (2.1 g) in 75 ml of anhydrous pyridine was heated to 80° C. with stirring under N2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826846 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-9b35111e0739403790f35b6f39432f2a |
| Source note | uspto-grants-1989_05 |