HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Permanganate → 5-Cyano-6-methoxypicolinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Permanganate | HCID 516875 | — |
| Reactant | 2-Methoxy-6-methylnicotinonitrile | HCID 5323803 | — |
| Reactant | Isopropanol-hcl-water | HCID 21409480 | — |
| Product | 5-Cyano-6-methoxypicolinic acid | HCID 13650104 | — |
Reaction Steps
3-Cyano-2-methoxy-6-methylpyridine is oxidised with potassium permanganate in aqueous solution to give 5-cyano-6-methoxypyridine-2-carboxylic acid (m.p. 235°-237° C.), subsequent hydrogenation of which on palladium/charcoal in isopropanol/water/hydrochloric acid gives the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826858 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-265e4db7ac3141999db4c614009fc41b |
| Source note | uspto-grants-1989_05 |