HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → HCID 13192414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 1,1'-Thiocarbonyldiimidazole | HCID 80264 | — |
| Reactant | HCID 10537963 | HCID 10537963 | — |
| Product | HCID 13192414 | HCID 13192414 | 74.7% |
Reaction Steps
By reaction of 9,10-didehydro-6-methylergoline-8β-amine with 1,1'-thiocarbonyldiimidazole and diethylamine analogously to Example 11, 3-(9,10-didehydro-6-methyl-8β-ergolinyl)-1,1-diethylthiourea is obtained, mp 207° C. (decomposition) and, respectively, therefrom the hydrogen maleate in a 74.7% yield (based on the 8β-amine), mp 180° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826852 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-88c913f2e05846fca33f7ad58a3f22bc |
| Source note | uspto-grants-1989_05 |