HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 18632309, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 2-Bromo-5,6-dimethoxy-indan-1-one | HCID 10923631 | — |
| Reactant | HCID 21242108 | HCID 21242108 | — |
| Solvent | Chloroform ether | HCID 21911965 | — |
| Product | HCID 18632309 | HCID 18632309 | 54.7% |
Reaction Steps
Prepared from 4-(2-methyl-1-benzimidazolinyl)-piperidine hydrochloride hydrobromide and 2-bromo-5,6-dimethoxy-1-indanone without isolation of the intermediate ketone and using NaBH4 as the hydrogenating agent. Yield 54.7%; m.p. 255°-256° C. (chloroform/diethyl ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826975 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-b4a457abb48246209042232de91940a3 |
| Source note | uspto-grants-1989_05 |