HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1761647Generated: November 1, 2026
Sulfuric Acid → 3-Bromo-2,4,5-trifluorobenzoic acid
https://huagongshe.com/reaction/1761647
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 3-Bromo-2,4,5-trifluorobenzamide | HCID 13748801 | — |
| Product | 3-Bromo-2,4,5-trifluorobenzoic acid | HCID 2783246 | — |
Reaction Steps
A mixture of 3-bromo-2,4,5-trifluorobenzamide (8.7 g) and 18N-sulfuric acid (50 ml) was stirred at 100° C. for 4 hours, and then poured into ice water (200 ml). The resulting precipitate was collected by filtration and recrystallized from dichloro-methane-n-hexane to give the title compound (6.9 g), mp 125°-127° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04826982 |
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| Source dataset | uspto-grants-1989_05 |
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| ORD ID | ord-1740de5887144befa7cbdfabb2cab21c |
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| Source note | uspto-grants-1989_05 |
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