HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1761651Generated: November 2, 2026
Acetic Anhydride → Ethyl 2-(3-bromo-2,4,5-trifluorobenzoyl)-3-ethoxyacrylate
https://huagongshe.com/reaction/1761651
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Ethyl 3-bromo-2,4,5-trifluorobenzoylacetate | HCID 10592111 | — |
| Reactant | Ethylorthoformate | HCID 53630039 | — |
| Product | Ethyl 2-(3-bromo-2,4,5-trifluorobenzoyl)-3-ethoxyacrylate | HCID 54232143 | 99.5% |
Reaction Steps
A mixture of ethyl 3-bromo-2,4,5-trifluorobenzoylacetate (1.5 g), ethyl orthoformate (1.0 g) and acetic anhydride (1.2 g) was stirred at 130° C. for 4.5 hours and then concentrated to give the title compound (1.75 g) as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04826982 |
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| Source dataset | uspto-grants-1989_05 |
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| ORD ID | ord-3df0a3e839aa47b588a6a3e3ad71faaa |
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| Source note | uspto-grants-1989_05 |
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