HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitromethane → Cyclohexanone, 3-(nitromethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | 4-Nonene | HCID 94226 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | Cyclohexanone, 3-(nitromethyl)- | HCID 10920766 | 100% |
Reaction Steps
21.9 g of cyclohexanone are left to stand together with 175 ml of nitromethane and 2.1 g of 5-diazabicyclo[4.3.0.]non-5-ene (DBN) in 250 ml of isopropanol at room temperature for 2 days. The working up is carried out in analogy to the procedure for Example 1 and provides 37.2 g (100% of theory) of 3-(nitromethyl)cyclohexanone which is pure enough for the next reaction. Rf =0.62 CH2Cl2 :CH3OH=99:1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04827032 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-f55e579a95334855ba8e938e15edb14b |
| Source note | uspto-grants-1989_05 |