2-Mercaptoethanol → HCID 21242306, compound

Participants

Reaction Steps

A solution of 4.1 g (0.016 mol) of (E,E)-3,7,11-trimethyl-10-oxo-2,6,11-dodecatrienamide in 125 ml of methanol is treated with 3.5 ml of 2-mercaptoethanol and 7 ml of triethylamine. The solution is stirred at room temperature for 18 hours. After removing the solvent the residue is taken up three times in toluene and freed from solvent on a rotary evaporator. The residue is chromatographed on silica gel with ether-methanol 10:1. There is obtained (2E,6E)-12-(2-hydroxyethyl)-3,7,11-trimethyl-10-oxo-2,6-dodecadienamide which exhibits the following absorption bands in the IR spectrum: 3340 cm-1, 3201 cm-1, 2924 cm-1, 1707 cm-1, 1669 cm-1, 1608 cm-1, 1409 cm-1, 1369 cm-1, 1305 cm-1, 1046 cm-1, 1012 cm-1.

Provenance & Evidence