Benzyl Chloride → 4-Benzylthioquinazoline

HRID 1761857Notes

Reaction equation

HRID 1761857 reaction equation
[SH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH2:12](Cl)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:12]([S:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 7503Benzyl ChlorideHCID 178527884HCID 178527884, compound

Product 1

HCID 2483464-BenzylthioquinazolineYield 47.8%

Procedure

The title compound(5.2 g) was prepared from 4-mercaptoquinazoline(7.0 g) and benzyl chloride(5.5 g).

Sources & evidence

ORD record
ord-2cd1a2e9ca0443fca86548a7200df84e
Source dataset
uspto-grants-1989_05
Patent number
US04829069

Reaction notes

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