2-(Chloromethyl)furan → 4-(Furan-2-ylmethylsulfanyl)quinazoline

HRID 1761858Notes

Reaction equation

HRID 1761858 reaction equation
[SH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1.Cl[CH2:13][C:14]1[O:15][CH:16]=[CH:17][CH:18]=1>>[O:15]1[CH:16]=[CH:17][CH:18]=[C:14]1[CH2:13][S:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 2195202-(Chloromethyl)furanHCID 178527884HCID 178527884, compound

Product 1

HCID 2483484-(Furan-2-ylmethylsulfanyl)quinazolineYield 49.4%

Procedure

The title compound(3.69 g) was prepared from 4-mercaptoquinazoline(5.0 g) and 2-chloromethylfuran(5.4 g).

Sources & evidence

ORD record
ord-372df5dbb28f48ff9b676b2304774745
Source dataset
uspto-grants-1989_05
Patent number
US04829069

Reaction notes

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