5-(Chloromethyl)-1,2,3-trimethoxybenzene → HCID 14479908, compound

HRID 1761860Notes

Reaction equation

HRID 1761860 reaction equation
[SH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23])[CH2:17]Cl>>[CH3:25][O:24][C:20]1[CH:19]=[C:16]([CH:15]=[C:14]([O:13][CH3:12])[C:21]=1[O:22][CH3:23])[CH2:17][S:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 774485-(Chloromethyl)-1,2,3-trimethoxybenzeneHCID 178527884HCID 178527884, compound

Product 1

HCID 14479908HCID 14479908, compoundYield 42.2%

Procedure

The title compound(3.56 g) was prepared from 4-mercaptoquinazoline(4.0 g) and 3,4,5-trimethoxybenzyl chloride(7.3 g).

Sources & evidence

ORD record
ord-2299332d38b04731b868e5b079d356ae
Source dataset
uspto-grants-1989_05
Patent number
US04829069

Reaction notes

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