Benzenesulfonyl chloride → HCID 20043757, compound

Participants

Reaction Conditions

Reaction Steps

The operation is done as in example 49, starting with 0.80 g of 5-(2-propenyloxy)pyrrolidin-2-one. After cooling to -10° C., a solution of 1.00 g of benzenesulphonyl chloride in 10 cm3 of anhydrous ether is added and the temperature is maintained at -10° C. 100 cm3 of ethyl acetate is added before filtering. Elution is done with a mixture of ethyl acetate and hexane (1-1) and by re-crystallizing from isopropyl ether, 0.20 g of product is obtained, m.p. 54°-56° C.

Provenance & Evidence