1,2-Dibromoethane → HCID 14125894, compound

Participants

Reaction Steps

20.7 g (0.1 mol) of (1, 2, 4-triazol-1-yl)-methyl 1-naphthyl ketone in 100 ml of dichloroethane, 0.3 g of benzyltriethyl-ammonium chloride and 27 ml of 50% strength sodium hydroxide solution were placed in a reaction flask, and, under reflux, 20.7 g (0.11 mol) of 1, 2-dibromoethane were added dropwise over 15 minutes. The mixture was refluxed for a further 5 hours, cooled, diluted with water and extracted with di-chloroethane. After drying and removing the solvent, 10.6 g (45% of theory) of the title compound were obtained as an oil.

Provenance & Evidence