HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → Methyl 3-formyl-2-(4-nitrobenzyloxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | Methyl 3-formyl-2-hydroxybenzoate | HCID 345559 | — |
| Solvent | Water | HCID 962 | — |
| Product | Methyl 3-formyl-2-(4-nitrobenzyloxy)benzoate | HCID 20043641 | 99.4% |
Reaction Steps
A mixture of 5.0 g of methyl 3-formyl-2-hydroxybenzoate, 11.7 g of 4-nitrobenzyl bromide, 11.7 g of potassium carbonate and 70 ml of dimethylformamide is stirred at room temperature for 1 hour. The reaction mixture is poured into water and the aqueous mixture is extracted with ethyl acetate. The extract is dried and evaporated to remove solvent to give 8.70 g of methyl 3-formyl-2-(4-nitrobenzyloxy)benzoate as colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04829067 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-7b9e0f0d8a6743c392008a68cad4bc78 |
| Source note | uspto-grants-1989_05 |