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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1761943Generated: October 26, 2026

2,3-Epoxy-2-methyl-1,4-naphthoquinone → Menadione

https://huagongshe.com/reaction/1761943

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Epoxy-2-methyl-1,4-naphthoquinoneHCID 85845—
SolventEthanolHCID 702—
ProductMenadioneHCID 4055—

Reaction Steps

According to Flowchart V, 2,3-epoxy-2-methyl-1,4-naphthoquinone 11 is reacted with an amine 2, where R2, R3, R4 and R5 are as described above, in absolute ethanol with heat for several hours, producing the 3-methyl-1,4-naphthalenedione derivatives 12.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04829089
Source datasetuspto-grants-1989_05
ORD IDord-110e8847ed57466e940996af7eb8f823
Source noteuspto-grants-1989_05