HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Trifluoromethylbenzenesulphonyl chloride → 1-(3-Chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-4-[[2-(trifluoromethyl)phenyl]sulfonyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Trifluoromethylbenzenesulphonyl chloride | HCID 136616 | — |
| Reactant | 1,4-Naphthalenedione, 2-chloro-3-(1-piperazinyl)- | HCID 699794 | — |
| Product | 1-(3-Chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-4-[[2-(trifluoromethyl)phenyl]sulfonyl]piperazine | HCID 13934779 | — |
Reaction Steps
A 1.5 g portion of 3-chloro-2-piperazinyl-1,4-naphthoquinone and 1.26 g of 2-trifluoromethylbenzenesulfonyl chloride were reacted as described in Example 56, giving 1.53 g of the desired product, mp 122°-124° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04829089 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-6c012ec0145c492480c91324940c1143 |
| Source note | uspto-grants-1989_05 |