HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyphenylacetic acid → HCID 23369910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyphenylacetic acid | HCID 127 | — |
| Reactant | Benzene | HCID 241 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Cyclohexanol | HCID 7966 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23369910 | HCID 23369910 | — |
Reaction Steps
A mixture of 4-hydroxyphenylacetic acid (7.6 g, 0.05 mol), cyclohexyl alcohol (6 g, 0.06 mol), p-toluenesulfonic acid (1 g, 0.006 mol) and benzene (300 mL) was refluxed with continuous water separation for 8 hours. The mixture was cooled and washed, first with aqueous 5% Na2CO3 solution, then twice with water, then was dried over anhydrous MgSO4. Evaporation of the solvent in vacuo gave cyclohexyl 4-hydroxyphenylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04829086 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-0ef5f49cd72e4643a0932890ba56c274 |
| Source note | uspto-grants-1989_05 |