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Tris(hydroxymethyl)aminomethane → 2-((6-Chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tris(hydroxymethyl)aminomethane | HCID 6503 | — |
| 反応物 | 6-Chrysenecarbaldehyde | HCID 12438774 | — |
| 反応物 | 2-((6-Chrysenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride | HCID 13375278 | — |
| 溶媒 | Diethyl ether methanol | HCID 21864698 | — |
| 生成物 | 2-((6-Chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride | HCID 13375340 | — |
反応手順
Using the reductive amination procedure described in 1B, 6-chrysenecarbaldehyde (1A) and tris(hydroxymethyl)aminomethane (Aldrich) gave 2-((6-chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride, mp 238°-239° (dec), (CH3OH/Et2O), (C, H, Cl, N).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04829090 |
| 出典データセット | uspto-grants-1989_05 |
| ORD ID | ord-004b871935234aa2bcdc1b46dae37621 |
| 出典メモ | uspto-grants-1989_05 |