Carbonate Ion → 2-Ethyl-1-methyl-6-[2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridin-7-yloxy]-1H-indole-3-carboxylic acid methylamide

HRID 176200Notes

Reaction equation

HRID 176200 reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[CH2:17]([CH3:18])[c:19]1[n:20]([CH3:33])[c:21]2[cH:22][c:23]([OH:32])[cH:24][cH:25][c:26]2[c:27]1[C:28](=[O:29])[NH:30][CH3:31].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:11]1[n:12]([CH3:16])[cH:13][cH:14][n:15]1)[s:10]2.[Cs+:38].[Cs+:39]>>[c:2]1([O:32][c:23]2[cH:22][c:21]3[n:20]([CH3:33])[c:19]([CH2:17][CH3:18])[c:27]([C:28](=[O:29])[NH:30][CH3:31])[c:26]3[cH:25][cH:24]2)[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:11]1[n:12]([CH3:16])[cH:13][cH:14][n:15]1)[s:10]2

Participants

5

Reactant 4

HCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 221435637-chloro-2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridineHCID 221436512-ethyl-6-hydroxy-N,1-dimethyl-1H-indole-3-carboxamide

Product 1

HCID 207677962-Ethyl-1-methyl-6-[2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridin-7-yloxy]-1H-indole-3-carboxylic acid methylamide

Sources & evidence

ORD record
ord-b7754f4d83304d539102b0dfc1f481fb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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