1,3,4-Thiadiazol-2-amine → HCID 14516780, compound

HRID 1762034Notes

Reaction equation

HRID 1762034 reaction equation
[NH2:1][CH:2]([C:8]#[N:9])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH:10]([O-])([O-])OCC.[NH2:16][C:17]1[S:18][CH:19]=[N:20][N:21]=1>>[NH2:9][C:8]1[N:16]([C:17]2[S:18][CH:19]=[N:20][N:21]=2)[CH:10]=[N:1][C:2]=1[C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

4

Reactant 3

HCID 199091,3,4-Thiadiazol-2-amineHCID 288716Ethyl 2-amino-2-cyanoacetateHCID 53630039Ethylorthoformate

Product 1

HCID 14516780HCID 14516780, compound

Procedure

The desired compound was synthesized following the procedures described in Reference Example 7 by using ethyl α-aminocyanoacetate, ethyl orthoformate and 2-amino-1,3,4-thiadiazole as raw materials. m.p.: 181° to 183° C.

Sources & evidence

ORD record
ord-1832273e29bd446e974a571875815391
Source dataset
uspto-grants-1989_05
Patent number
US04830660

Reaction notes

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