Hydrochloric Acid → HCID 20042126, compound

Participants

Reaction Steps

35.6 g (0.15 mol) of 6-amino-4,4-dimethyl-7-nitro-4H-3,1-benzoxazin-2-one are dissolved in 500 ml of methanol and 60 ml of 7.5 N methanolic hydrochloric acid, 3.5 g of 10% Palladium/charcoal are added and the resulting mixture is hydrogenated for 45 minutes in an autoclave at ambient temperature under 5 bar of hydrogen pressure. The catalyst is then removed by suction filtering and the filtrate is diluted to 2 liters with ether. The precipitate is suction filtered, washed with ether and dried.

Provenance & Evidence