反应详情

To a solution of ethyl 1,4-dihydro-2-methyl-4-(3-nitrophenyl)-6-phenyl-3-pyridinecarboxylate (0.5 g) in chloroform (5 ml) was added activated manganese dioxide (2 g) and the mixture was refluxed for 1 hour with stirring vigorously. After allowing to cool to ambient temperature, manganese dioxide was filtered off and the filtrate was evaporated in vacuo. The residual precipitates were recrystallized from ethanol, washed with ethanol and dried in vacuo to give ethyl 2-methyl-4-(3-nitrophenyl)-6-phenyl-3-pyridinecarboxylate (0.25 g).

1. temperaturethe mixture was refluxed for 1 hour
2. filtrationmanganese dioxide was filtered off
3. customthe filtrate was evaporated in vacuo
4. customThe residual precipitates
5. customwere recrystallized from ethanol
6. washwashed with ethanol
7. customdried in vacuo