HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Oxazolidineacetyl chloride, 2-oxo-4,5-diphenyl-, (4S,5R)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | [(4S,5R)-2-Oxo-4,5-diphenyl-1,3-oxazolidin-3-yl]acetic acid | HCID 58430307 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 3-Oxazolidineacetyl chloride, 2-oxo-4,5-diphenyl-, (4S,5R)- | HCID 10935977 | 100% |
Reaction Steps
A suspension composed of (4,5-cis-diphenyl-2-oxo-3-oxazolidinyl)acetic acid (29.1 g, 97.9 mmol), oxalyl chloride (18.6 g, 147 mmol) and benzene (120 ml) was refluxed for 2 hours. When the suspension became homogeneous, the solvent was distilled off. By the above procedure there was obtained the title compound (30.9 g) as light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04831026 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-aa46dd4435d04b2cb110922d77ee3904 |
| Source note | uspto-grants-1989_05 |