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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 176217Generated: November 1, 2026

2-Bromopyrimidine → N-(4-ethoxy-1-pyrimidin-2-ylpyrrolidin-3-yl)-3,6-diethyl-5-[6-methoxy-2-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine

https://huagongshe.com/reaction/176217

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopyrimidineHCID 78345—
Reactant5-(2,4-dichlorophenyl)-N-[4-ethoxy-1-(1,3-thiazol-2-yl)pyrrolidin-3-yl]-3,6-diethylpyrazin-2-amineHCID 73100485—
ReactantN-(4-ethoxypyrrolidin-3-yl)-3,6-diethyl-5-[6-methoxy-2-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amineHCID 178467178—
ProductN-(4-ethoxy-1-pyrimidin-2-ylpyrrolidin-3-yl)-3,6-diethyl-5-[6-methoxy-2-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amineHCID 72972474—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-f935b67563384e2e95c7780c24a336a9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)