反应详情

4-[2-(4-Chlorobenzamido)ethoxy]benzoic acid (3.19 g) was dissolved in 50 ml of methanol. A solution of 0.40 g of sodium hydroxide in 5 ml of water was added to the above methanolic solution, the mixture was concentrated in vacuo, the crystallised residue was recrystallised from methanol, and 2.30 g of crystalline product was obtained. M.p. not lower than 300° C.

1. concentrationthe mixture was concentrated in vacuo
2. customthe crystallised residue was recrystallised from methanol