HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → N-[4-(hydroxymethyl)-3-methylphenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | N-(4-Formyl-3-methylphenyl)acetamide | HCID 12931765 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[4-(hydroxymethyl)-3-methylphenyl]acetamide | HCID 54053024 | 85.1% |
Reaction Steps
Sodium borohydride (0.248 g) was added portionwise to a solution of 4-acetamido-2-methyl benzaldehyde (2.58 g) in methanol (26 ml) with ice-cooling. After being stirred for 3 hours, the mixture was evaporated in vacuo and the residue was washed with water and dried to give 4-acetamido-2-methylbenzyl alcohol (2.22 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04831041 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-d194634adfe44627bfb441d2d55db725 |
| Source note | uspto-grants-1989_05 |