Thionyl Chloride → HCID 14368348, compound

HRID 1762200Notes

Reaction equation

HRID 1762200 reaction equation
[CH3:1][C:2]1[C:7]([CH2:8]O)=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>C(Cl)Cl>[CH3:1][C:2]1[C:7]([CH2:8][Cl:16])=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 143684562-Methyl-6-ureidobenzyl alcohol

Product 1

HCID 14368348HCID 14368348, compoundYield 59.9%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 6-methyl-2-ureidobenzyl alcohol (1 g) and thionyl chloride (0.66 g) in methylene chloride (20 ml) was stirred for 2 hours at room temperature and evaporated in vacuo. The residue was washed with water and dried in a desiccator to give 6-methyl-2-ureidobenzyl chloride (0.66 g).

Workup

  1. customevaporated in vacuo
  2. washThe residue was washed with water
  3. customdried in a desiccator

Sources & evidence

ORD record
ord-b93b6c06c59747348eeaa8e72a8f001b
Source dataset
uspto-grants-1989_05
Patent number
US04831041

Reaction notes

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