Thionyl Chloride → HCID 14368440, compound

HRID 1762204Notes

Reaction equation

HRID 1762204 reaction equation
O[CH2:2][C:3]1[CH:19]=[CH:18][CH:17]=[CH:16][C:4]=1[CH2:5][O:6][C:7]1[C:8]([N+:13]([O-:15])=[O:14])=[N:9][CH:10]=[CH:11][CH:12]=1.S(Cl)([Cl:22])=O>ClCCl>[Cl:22][CH2:2][C:3]1[CH:19]=[CH:18][CH:17]=[CH:16][C:4]=1[CH2:5][O:6][C:7]1[C:8]([N+:13]([O-:15])=[O:14])=[N:9][CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 14368441HCID 14368441, compound

Product 1

HCID 14368440HCID 14368440, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 3-(2-hydroxymethylbenzyloxy)-2-nitropyridine (4.09 g) in dichloromethane (40 ml) was added thionyl chloride (0.24 ml) and the mixture was stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure to give 3-(2-chloromethylbenzyloxy)-2-nitropyridine (4.10 g).

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-19fcc1947d8a46109bfe5f0ad0c8e1be
Source dataset
uspto-grants-1989_05
Patent number
US04831041

Reaction notes

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