Benzoyl chloride → HCID 13651303, compound

Participants

Reaction Steps

377 g (2 moles) of 2-amino-4-chloro-5-nitrophenol and 280 ml (2 moles) of triethylamine were added to 1 liter of N,N-dimethylacetoamide, followed by dropping 281 g (2 moles) of benzoyl chloride at about 50° C. in about 30 minutes. After continuing the agitation for further 30 minutes, 1 liter of methanol and 1 liter of water were added to the reaction solution. The resulting crystals were filtered and washed with 1 liter of methanol, thereby obtaining 547 g (yield 94%) of captioned benzoate compound. m.p. 207°-210° C., IR spectrum νC=0, 1725 cm-1.

Provenance & Evidence