HCID 20042935, compound → HCID 136336903, compound

HRID 1762359Notes

Reaction equation

HRID 1762359 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][N:9]([C:12]2[CH:19]=[CH:18][C:15]([CH:16]=O)=[CH:14][CH:13]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[C:20]([O-:23])(=[O:22])[CH3:21].[NH2:24][N+:25]1[CH:29]=[CH:28][N:27]([NH2:30])[C:26]=1[CH2:31][CH3:32]>C(O)(=O)C.C(O)C>[C:20]([O-:23])(=[O:22])[CH3:21].[C:20]([O-:23])(=[O:22])[CH3:21].[C:20]([O-:23])(=[O:22])[CH3:21].[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][N:9]([C:12]2[CH:19]=[CH:18][C:15]([CH:16]=[N:24][N+:25]3[CH:29]=[CH:28][NH:27][C:26]=3[CH2:31][CH3:32])=[CH:14][CH:13]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][N:9]([C:12]2[CH:13]=[CH:14][C:15]([CH:16]=[N:30][N+:27]3[CH:28]=[CH:29][NH:25][C:26]=3[CH2:31][CH3:32])=[CH:18][CH:19]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][N:9]([C:12]2[CH:19]=[CH:18][C:15]([CH:16]=[N:24][N+:25]3[CH:29]=[CH:28][NH:27][C:26]=3[CH2:31][CH3:32])=[CH:14][CH:13]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

5

Reactant 2

HCID 20042935HCID 20042935, compoundHCID 70351932HCID 70351932, compound

Product 1

HCID 136336903HCID 136336903, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 702EthanolSolvent

Procedure

1.95 g (7.4 mmol) of p-[4-(ethoxycarbonyl)-1-piperazinyl]benzaldehyde are added to a solution of 0.69 g (3.7 mmol) of 1,3-diamino-2-ethyl-imidazolium acetate in 10 ml of glacial acetic acid, the mixture is left to stand at room temperature for 18 hours, then diluted with 30 ml of ethanol and the product is crystallized out by the addition of ether. There is obtained 1,3-bis[[[p-(4-(ethoxycarbonyl)-1-piperazinyl]benzylidene]amino]-2-ethyl-imidazolium acetate diacetate of melting point 187°-188°.

Workup

  1. waitthe mixture is left
  2. customthe product is crystallized out by the addition of ether

Sources & evidence

ORD record
ord-f5d200ac6b2541dcb670823bf8803799
Source dataset
uspto-grants-1989_05
Patent number
US04831151

Reaction notes

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