2-Bromo-1-(3,4,5-trimethoxyphenyl)ethanone → HCID 178437692, 화합물

HRID 1762373노트

반응식

HRID 1762373 반응식
[CH3:1][N:2]([CH3:18])[C:3]1[CH:17]=[CH:16][C:6]([CH:7]=[N:8][N:9]2[CH:13]=[CH:12][N:11]=[C:10]2[CH2:14][CH3:15])=[CH:5][CH:4]=1.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:28]=[C:29]([O:33][CH3:34])[C:30]=1[O:31][CH3:32])[C:24](=[O:27])[CH2:25][Br:26]>C(Cl)Cl>[Br-:26].[CH3:18][N:2]([CH3:1])[C:3]1[CH:4]=[CH:5][C:6]([CH:7]=[N:8][N+:9]2[CH:13]=[CH:12][N:11]([CH2:25][C:24]([C:23]3[CH:28]=[C:29]([O:33][CH3:34])[C:30]([O:31][CH3:32])=[C:21]([O:20][CH3:19])[CH:22]=3)=[O:27])[C:10]=2[CH2:14][CH3:15])=[CH:16][CH:17]=1

참가 물질

4

반응물 2

HCID 36857322-Bromo-1-(3,4,5-trimethoxyphenyl)ethanoneHCID 545500571-[[p-(Dimethylamino)benzylidene]amino]-2-ethylimidazole

생성물 1

HCID 178437692HCID 178437692, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

1.44 g (6 mmol) of 1-[[p-(dimethylamino)benzylidene]-amino]-2-ethylimidazole are dissolved in 20 ml of methylene chloride. The solution is treated with 1.72 g (6 mmol) of 3,4,5-trimethoxyphenacyl bromide and left to stand at room temperature for 46 hours. The product is crystallized out by the addition of ether and recrystallized from ethanol. There is obtained 1-[[p-(dimethylamino)benzylidene]amino]-2-ethyl-3-(3,4,5-trimethoxyphenacyl)-imidazolium bromide of melting point 232° (decomposition).

후처리

  1. waitleft
  2. customThe product is crystallized out by the addition of ether
  3. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-5187f4b762794ac78fbbcd3371a7d188
출처 데이터셋
uspto-grants-1989_05
특허 번호
US04831151

반응 노트

불러오는 중…