4-(Dimethylamino)Benzaldehyde → HCID 70391578, compound

Participants

Reaction Steps

0.985 g (5 mmol) of 1,3-diamino-4-(chloromethyl)-2-methylimidazolium chloride and 7.45 g (50 mmol) of 4-dimethylaminobenzaldehyde are dissolved in 250 ml of glacial acetic acid. The solution is left to stand at room temperature for 36 hours and evaporated. The residue is placed on a column loaded with 150 g of silica gel (particle size 0.063-0.2 mm) and the product is eluted with chloroform/methanol (9:1). The eluate is evaporated and the product is crystallized from ethanol/ether. There is obtained 1,3-bis[[p-(dimethylamino)benzylidene]amino]-4-(chloromethyl)-2-methylimidazolium chloride of melting point 188° (dec.)

Provenance & Evidence