Ethanolamine → HCID 20040901, compound

HRID 1762441Notes

Reaction equation

HRID 1762441 reaction equation
[CH2:1]([CH2:3][NH2:4])[OH:2].Cl[C:6]1[CH:11]=[C:10]([CH3:12])[N:9]=[C:8]2[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[O:22][CH3:23])=[N:14][NH:15][C:7]=12>>[OH:2][CH2:1][CH2:3][NH:4][C:6]1[CH:11]=[C:10]([CH3:12])[N:9]=[C:8]2[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[O:22][CH3:23])=[N:14][NH:15][C:7]=12

Participants

3

Reactant 2

HCID 700EthanolamineHCID 178489371HCID 178489371, compound

Product 1

HCID 20040901HCID 20040901, compound

Procedure

The title compound was prepared form ethanolamine and 7-chloro-5-methyl-3-(methoxyphenyl)-1H-pyrazolo[4,3-b]pyridine (D13) in an analogous manner to the preparation of Example 2 giving a pale yellow solid, m.p. 193°-194° C. Ratio of meta and para isomer 1:2

Workup

  1. customto the preparation of Example 2 giving a pale yellow solid, m.p. 193°-194° C

Sources & evidence

ORD record
ord-c5cd10a80fa742c68aa0531a064171e8
Source dataset
uspto-grants-1989_05
Patent number
US04833136

Reaction notes

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