Ethyl chloroformate → HCID 54275606, compound

Participants

Reaction Steps

Ethyl chloroformate (0.44 ml) was added slowly to a suspension of the product of Stage (ii) (0.8 g) and diisopropylethylamine (1.0 ml) in freshly distilled tetrahydrofuran (50 ml). The mixture was stirred at room temperature for 24 h and then reduced to dryness. The residue was chromatographed on silica (D) to give the title compound as an oil (0.4 g). T.l.c. SiO2 : ethyl acetate, Rf. 0.80 (Ceric).

Provenance & Evidence