反应详情

To a solution of the product from Example 81 (3.0 g.) in methanol (60 ml.), 1N sodium hydroxide (60 ml.) is added. After 4 hours, the solution is applied to a column of Dowex 50 ion exchange resin in the hydrogen cycle, and the desired material is eluted with water to yield 2.3 g. of the named product Rf : 0.2 (silica gel-benzene:acetic acid, 75:25).

1. washthe desired material is eluted with water
2. customto yield 2.3 g