HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-propanol → HCID 13747689, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-propanol | HCID 31370 | — |
| Reactant | 3-Methylxanthine | HCID 70639 | — |
| Reactant | 1-Chloro-5-hydroxy-5-methylhexane | HCID 13747679 | — |
| Product | HCID 13747689 | HCID 13747689 | — |
Reaction Steps
It was also possible to build up the compound starting from 3-methylxanthine in a two-stage reaction sequence, by first introducing the 2-hydroxypropyl group into the 7-position (melting point: 278°-280° C.; yield: 69.6% of theory) with 1-chloro-2-propanol and then alkylating the product in the 1-position (yield: 67.5% of theory) with 1-chloro-5-hydroxy-5-methylhexane (Example 1a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04833146 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-ec66bc4135db4175af4f5c463a467f34 |
| Source note | uspto-grants-1989_05 |