7-Benzyl-3-methylxanthine → A 802715

HRID 1762545Notes

Reaction equation

HRID 1762545 reaction equation
C(N1C2C(=[O:17])NC(=O)N(C)C=2N=C1)C1C=CC=CC=1.CN1C2N=CN(CCC)C=2C(=O)NC1=O.[CH3:35][N:36]1[C:44]2[N:43]=[CH:42][N:41]([CH2:45][CH2:46][CH3:47])[C:40]=2[C:39](=[O:48])[N:38]([CH2:49][CH2:50][CH2:51][CH:52]=[C:53]([CH3:55])[CH3:54])[C:37]1=[O:56]>>[OH:17][C:53]([CH3:55])([CH3:54])[CH2:52][CH2:51][CH2:50][CH2:49][N:38]1[C:39](=[O:48])[C:40]2[N:41]([CH2:45][CH2:46][CH3:47])[CH:42]=[N:43][C:44]=2[N:36]([CH3:35])[C:37]1=[O:56]

Participants

4

Reactant 3

HCID 6856307-Benzyl-3-methylxanthineHCID 33143973-Methyl-7-propylpurine-2,6-dioneHCID 200411283-Methyl-1-(5-methyl-4-hexenyl)-7-propylxanthine

Product 1

HCID 129959A 802715

Procedure

The same compound was obtained, inter alia, by alkylation of the compound of Example 6 with 1-bromo- or 1-chloropropane analogously to Example 3, by reaction of 3-methyl-7-propylxanthine with the tertiary alcohol of Example 1a analogously to Example 2, or by acid-catalyzed hydration of 3-methyl-1-(5-methyl-4-hexenyl)-7-propylxanthine analogously to Example 14 below.

Workup

  1. customThe same compound was obtained

Sources & evidence

ORD record
ord-bad931619c524789b8a38274bc82424e
Source dataset
uspto-grants-1989_05
Patent number
US04833146

Reaction notes

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