HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R)-1-(3-phenoxyphenyl)ethan-1-ol → 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R)-1-(3-phenoxyphenyl)ethan-1-ol | HCID 22815813 | — |
| Reactant | 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid | HCID 54570584 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid | HCID 54570584 | — |
| Product | 2,2-Dimethyl-3-(3-ethoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate | HCID 73865272 | — |
Reaction Steps
Using the procedure of Example 9, (1R, cis, ΔZ) 2,2-dimethyl-3-(3-ethoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid and 1(R)-(3-phenoxyphenyl)-ethanol were reacted to obtain 1(R)-(3-phenoxyphenyl)-ethyl (1R, cis, ΔZ) 2,2-dimethyl-3-(3-ethoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate with a specific rotation of [α]D20 =+145°±2.5° (c=1% in benzene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04833163 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-726eed7c12d34304be3d130ba199fc1c |
| Source note | uspto-grants-1989_05 |