HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid → 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid | HCID 54570584 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid | HCID 54570584 | — |
| Product | 2,2-Dimethyl-3-(3-methoxy-3-oxo-1-propeny)-cyclopropane-carboxylate | HCID 86743070 | — |
Reaction Steps
Using the procedure of Example 9, (1R, cis ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid and (RS) α-cyano-(3-benzoyl-phenyl)-methanol were reacted to obtain (RS) α-cyano-(3-benzoyl-phenyl)-methyl (1R, cis ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate with a specific rotation of [α]D20 =+43°±1° (c=1% in toluene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04833163 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-a712b2e3a15f442297e131904e4015bf |
| Source note | uspto-grants-1989_05 |