HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,4,5,6-Pentafluorobenzyl Alcohol → 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,4,5,6-Pentafluorobenzyl Alcohol | HCID 9923 | — |
| Reactant | 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid | HCID 54570584 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid | HCID 54570584 | — |
| Product | 2,2-Dimethyl-3-(3-methoxy-3-oxo-1-propeny)-cyclopropane-carboxylate | HCID 86743070 | — |
Reaction Steps
Using the procedure of Example 9, (1R, cis, ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid and (2,3,4,5,6-pentafluorophenyl)-methanol were reacted to obtain (2,3,4,5,6-pentafluoro-phenyl)methyl (1R, cis, ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate with a specific rotation of [α]D20 =+29.5°±2° (c=0.8% in chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04833163 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-24f75afc5a2646d19d9852ef174bb0f1 |
| Source note | uspto-grants-1989_05 |