(2-Phenoxy-5-thiazolyl)-methanol → 2,2-Dimethyl-3-(3-cyclopropylmethoxy-3-oxo-1-propenyl) cyclopropane-carboxylic acid

Participants

Reaction Steps

Using the procedure of Example 9, the product of Step B and (1R, cis ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)cyclopropane-carboxylic acid were reacted to obtain (2-phenoxy-5-thiazolyl)-methyl (1R, cis, ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate melting at 62° C. and havng a specific rotation of [α]D20 =+60.5°±1.5° (c=1.5% in benzene).

Provenance & Evidence