HCID 20039822, compound → HCID 20039823, compound

HRID 1762835Notes

Reaction equation

HRID 1762835 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[CH2:15][CH2:14][N:13]([C:16]3[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=3)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[CH2:11][CH2:12][N:13]([C:16]3[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=3)[CH2:14][CH2:15]2)=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 20039822HCID 20039822, compound

Product 1

HCID 20039823HCID 20039823, compoundYield 97.9%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of the product from part (i) (0.24 g) and 5% palladium/carbon (25 mg) in methanol (20 ml) was hydrogenated at 3.5 bars and 21° for 3 hours. The catalyst was filtered off and the filtrate was evaporated to give the title compound, (0.21 g), m.p. 196°-197° (from ethyl acetate/hexane).

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-f86f512262d64be496665898dc252e29
Source dataset
uspto-grants-1989_05
Patent number
US04835165

Reaction notes

Loading…