Ammonia → 4-(1-Acetylpiperidin-4-yl)benzenesulphonamide

Participants

Reaction Steps

The product of (i) above (21.0 g) was added portionwise to a stirred mixture of concentrated aqueous ammonia solution (160 ml) and ethanol (160 ml). The mixture was warmed at 35° until solution was complete and then evaporated. The residue was triturated with water and the solid was filtered off and dried to give the title compound, (18.0 g), m.p. 196°-197° (from ethanol).

Provenance & Evidence